hrp0084p2-422 | GH & IGF | ESPE2015

Physical Performance and Right Ventricular Function in Children with GH Deficiency before and after 12 Months-GH Replacement Therapy

Barbieri Flavia , Capalbo Donatella , Lucci Rosa , Vitelli Alessandra , Esposito Andrea , Di Pietro Elisa , Rapacciuolo Antonio , Vigorito Carlo , Salerno Mariacarolina

Background: Several metabolic abnormalities, including unfavourable lipid profile, impaired cardiac performance, muscle strength and endurance capacity have been documented in GH Deficiency (GHD) adults. Alterations in cardiac morphology and left ventricular function and early markers of cardiovascular risk have been also detected in GHD children; however, no studies have so far investigated the effects of GHD on physical performance and right ventricular (RV) function in chil...